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Department of Veterinary Pathobiology

The Department of Veterinary Pathobiology (VPB) was created by the mergers of the Departments of Veterinary Pathology and Veterinary Microbiology. VPB is an integral component of the College of Veterinary Medicine that provides a unique and critical link between the basic and clinical sciences. Our mission is to acquire, advance and disseminate knowledge in the fields of pathology, parasitology, microbiology, immunology, comparative medicine, genetics and related disciplines that will ultimately lead to better diagnosis, control and prevention of animal and human diseases and to provide training of the next generation of researcher scientists. We integrate this knowledge into the teaching, research and service programs within the college and across our campus.

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The goals of our service component are to provide quality, state-of-the-art diagnostic service to veterinarians, animal owners, academia and private industry through the activities of the Veterinary Medical Diagnostic Laboratory. Through our service activities, we strive to identify the causes of new diseases, to promote the health of agricultural, companion and research animals, and to enhance the animal industry, both in Missouri and globally.

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Critical to the Department's interests in infectious diseases and vector-borne diseases research, the recent construction of an NIH-funded Laboratory for Infectious Diseases Research (LIDR) provides modern BSL-3 containment laboratory space and animal holding facilities for the investigation of highly infectious organisms and human Select Agents. This facility permits MU researchers to explore studies on pathogenesis of high consequence pathogens with the goal of developing better diagnostics, treatments, and vaccines. Microscopy, Flow Cytometry, and Aerobiology core laboratories are available in this biocontainment facility. Additionally, MU has partnered with NIH to strategically invest in critical research resources, including unique resource centers for mouse, rat and swine genetic models for disease research and the development of transgenic and knockout animal strains. MU has supported the development of state of the art Research Core Facilities, to give MU investigators the research and training tools needed to develop nationally competitive research programs and teams.

Whether you are seeking to pursue a graduate degree, postdoctoral training, or are looking for information regarding our research or service expertise, I hope you find these pages helpful.

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Professor and Chair


 

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Alexander W.E. Franz

Alexander Franz, PhD won the 2014 award for best paper in the journal Insect Molecular Biology. Sponsored by the Royal Entomological Society, the award recognizes the best paper over a two-year period. The paper, “Transgene-mediated suppression of the RNA interference pathway in Aedes aegypti interferes with gene silencing and enhances Sindbis virus and dengue virus type 2 replication”. More recently, his laboratory was the first to report the use of CRISPR/Cas9 for genome editing in the mosquito vector, Aedes aegypti (PLoS One. 2015 Mar 27;10(3):e0122353. doi: 10.1371/journal.pone.0122353. eCollection 2015).

University of Missouri
College of Veterinary Medicine
©2012 Curators of the University of Missouri
An equal opportunity/ADA institution

 

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